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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
TGM-T28786-1mg | 1 mg |
7 - 10 business days* |
181.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM).... more
Product information "SJA6017"
Description: SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM). SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM). SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome. Target: Others. Smiles: S(N[C@H](C(N[C@@H](CC(C)C)C=O)=O)[C@@H](C)C)(=O)(=O)C1=CC=C(F)C=C1. References: Akdemir O, Uçankale M, Karaoglan A, Barut S, Sagmanligil A, Bilguvar K, Cirakoglu B, Sahan E, Colak A. Therapeutic efficacy of SJA6017, a calpain inhibitor, in rat spinal cord injury. J Clin Neurosci. 2008 Oct,15(10):1130-6. doi: 10.1016/j.jocn.2007.08.011. Epub 2008 Jul 24. PubMed PMID: 18656362.
Keywords: | Calpain Inhibitor 4, Calpain Inhibitor VI, Calpain-In-4, SJA 6017, SJA-6017 |
Supplier: | TargetMol |
Supplier-Nr: | T28786 |
Properties
Application: | Calpain-1/-2 inhibitor |
MW: | 372.45 D |
Formula: | C17H25FN2O4S |
Database Information
CAS : | 190274-53-4| Matching products |
KEGG ID : | K01367 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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