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Sinapyl alcohol is a monolignol and an aglycone form of syringin (Cay-22387) that has been found in Populus alba and has anti-inflammatory and antinociceptive activities. It is a precursor in the biosynthesis of lignin. Sinapyl alcohol (50, 100, and 200 µM) reduces LPS-induced production of nitrite, prostaglandin E2 (PGE2, Cay-14010), and TNF-alpha in RAW 264.7 cells. Sinapyl alcohol (20 and 30 mg/kg) inhibits acetic acid-induced writhing and increases the latency to paw licking in the hot plate test in mice.Formal Name: 4-(3-hydroxy-1-propen-1-yl)-2,6-dimethoxy-phenol. CAS Number: 537-33-7. Molecular Formula: C11H14O4. Formula Weight: 210.2. Purity: >95%. Formulation: (Request formulation change), A solid (stabilized with MEHQ, 0.2% w/w). Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 223, 276 nm. SMILES: OC1=C(OC)C=C(C=CCO)C=C1OC. InChi Code: InChI=1S/C11H14O4/c1-14-9-6-8(4-3-5-12)7-10(15-2)11(9)13/h3-4,6-7,12-13H,5H2,1-2H3. InChi Key: LZFOPEXOUVTGJS-UHFFFAOYSA-N. Origin: Synthetic.
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