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Description: SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3), and PB1(5) with Kds of 35 nM, 36 nM, 3.7 µM, 2.0 µM, and 13 nM, respectively. Target: Epigenetic Reader Domain. Smiles: CC(C)(C)OC(=O)N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O. References: Wanior M, et, al. Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J Med Chem. 2020 Dec 10,63(23):14680-14699.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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