Senaparib

Senaparib is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2.Formal Name: 5-fluoro-1-[[4-fluoro-3-[[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl]phenyl]methyl]-2,4(1H,3H)-quinazolinedione. CAS Number: 1401682-78-7. Synonyms: IMP-4297. Molecular Formula: C24H20F2N6O3. Formula Weight: 478.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 0.1 mg/ml. lambdamax: 219, 244 nm. SMILES: O=C1NC(N(CC2=CC=C(C(C(N3CCN(CC3)C4=NC=CC=N4)=O)=C2)F)C5=C1C(F)=CC=C5)=O. InChi Code: InChI=1S/C24H20F2N6O3/c25-17-6-5-15(14-32-19-4-1-3-18(26)20(19)21(33)29-24(32)35)13-16(17)22(34)30-9-11-31(12-10-30)23-27-7-2-8-28-23/h1-8,13H,9-12,14H2,(H,29,33,35). InChi Key: VBTUJTGLLREMNW-UHFFFAOYSA-N.