Selonsertib HCl

Item number	Size	Delivery time	Price
TGM-T70622-25mg	25 mg	7 - 10 business days*	1,971.00€
TGM-T70622-50mg	50 mg	7 - 10 business days*	2,583.00€
TGM-T70622-100mg	100 mg	7 - 10 business days*	3,404.00€

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Description: Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis... more

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Product information "Selonsertib HCl"

Description: Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation. Target: Others. Smiles: Cl.CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(c(C)cc2F)-n2cnc(c2)C2CC2)n1

Supplier:	TargetMol
Supplier-Nr:	T70622

Properties

Application:	pan-RAF inhibitor
MW:	481.96 D
Formula:	C24H25ClFN7O

Database Information

CAS :	1448428-05-4\| Matching products
KEGG ID :	K04365 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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