Scopoletin

Scopoletin is a natural coumarin found in a variety of plants, including some species from the genus Scopolia. Like esculetin (Cay-19286), scopoletin binds iron and is used by plants to acquire iron from alkaline soil. Scopoletin inhibits aldose reductase activity in galactose-fed rats, upregulates PPARgamma expression, and triggers phosphorylation of Nrf2 in animals.Formal Name: 7-hydroxy-6-methoxy-2H-1-benzopyran-2-one. CAS Number: 92-61-5. Synonyms: Esculetin 6-methyl ether, 7-Hydroxy-6-methoxycoumarin, 6-Methoxy-7-hydroxycoumarin, NSC 405647. Molecular Formula: C10H8O4. Formula Weight: 192.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 30 mg/ml, Ethanol: 2 mg/ml. lambdamax: 229, 254, 298, 346 nm. SMILES: O=C1C=CC2=CC(OC)=C(O)C=C2O1. InChi Code: InChI=1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3. InChi Key: RODXRVNMMDRFIK-UHFFFAOYSA-N.