SCH529074

Item number	Size	Delivery time	Price
TGM-T37042-1mg	1 mg	7 - 10 business days*	31.00€
TGM-T37042-2mg	2 mg	7 - 10 business days*	38.00€
TGM-T37042-5mg	5 mg	7 - 10 business days*	57.00€
TGM-T37042-1mL	1 ml	7 - 10 business days*	68.00€
TGM-T37042-10mg	10 mg	7 - 10 business days*	104.00€
TGM-T37042-25mg	25 mg	7 - 10 business days*	227.00€
TGM-T37042-50mg	50 mg	7 - 10 business days*	337.00€
TGM-T37042-100mg	100 mg	7 - 10 business days*	482.00€

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Description: SCH529074 is a selective activator of p53 (Ki = 1 µM) and can be used in studies... more

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Product information "SCH529074"

Description: SCH529074 is a selective activator of p53 (Ki = 1 µM) and can be used in studies about non-small-cell lung carcinoma. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. Target: p53. Smiles: CN(C)CCCNc1nc(CN2CCN(CC2)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)nc2ccccc12. References: Demma, M., Maxwell, E., Ramos, R., et al. SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding domain (DBD), restores growth-suppressive function to mutant p53 and interrupts HDM2-mediated ubiquitination of wild type p53. J. Biol. Chem. 285(14), 10198-10212 (2010).

Keywords:	SCH 529074
Supplier:	TargetMol
Supplier-Nr:	T37042

Properties

Application:	p53 activator
MW:	563.56 D
Formula:	C31H36Cl2N6

Database Information

CAS :	922150-11-6\| Matching products
KEGG ID :	K04451 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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