SB-265610
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610... more
Product information "SB-265610"
Description: SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively). Target: CXCR. Smiles: Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12. References: Auten RL, et al. Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats. J Pharmacol Exp Ther. 2001 Oct,299(1):90-5.
| Keywords: | GSK-CXCR2 |
| Supplier: | TargetMol |
| Supplier-Nr: | T16850 |
Properties
| Application: | Allosteric, inverse CXCR2 agonist |
| MW: | 357.16 D |
| Formula: | C14H9BrN6O |
Database Information
| CAS : | 211096-49-0| Matching products |
| KEGG ID : | K05050 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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