Savolitinib
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Larger quantity required? Request bulk
Description: Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally... more
Product information "Savolitinib"
Description: Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met). Target: c-Met/HGFR. Smiles: C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1. References: Jia H, et al. Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer. J Med Chem. 2014 Sep 25,57(18):7577-89.
| Keywords: | Volitinib, AZD-6094, HMPL-504 |
| Supplier: | TargetMol |
| Supplier-Nr: | TQ0210 |
Properties
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| MW: | 345.36 D |
| Formula: | C17H15N9 |
Database Information
| CAS : | 1313725-88-0| Matching products |
| KEGG ID : | K05099 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H361 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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