Sarcosine

Sarcosine is an intermediate in the biosynthesis of glycine from choline. It is a selective inhibitor of glycine transporter 1 (GlyT1) with IC50 values of 91 and greater than 1,000 µM for GlyT1 and GlyT2, respectively, in HEK293 cells expressing the human transporters. Sarcosine levels are increased in prostate cancer cell lines with an invasive phenotype compared with non-invasive cell lines. Sarcosine increases in a progressive fashion in prostate cancer with 0, 42, and 79% of benign, localized, and metastatic prostate tissue samples containing increased levels of sarcosine.Formal Name: N-methyl-glycine. CAS Number: 107-97-1. Molecular Formula: C3H7NO2. Formula Weight: 89.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: slightly soluble, PBS (pH 7.2): 10 mg/ml. SMILES: CNCC(O)=O. InChi Code: InChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6). InChi Key: FSYKKLYZXJSNPZ-UHFFFAOYSA-N.