SAR-20347
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SAR-20347 is an inhibitor of TYK2 and JAK1/2/3, with IC50 values of 0.6 nM, 23 nM,... more
Product information "SAR-20347"
Description: SAR-20347 is an inhibitor of TYK2 and JAK1/2/3, with IC50 values of 0.6 nM, 23 nM, 26 nM, and 41 nM, respectively. Target: Tyrosine Kinases, JAK. Smiles: NC(=O)c1nc(oc1Nc1ccc(cc1)C(=O)N1CCOCC1)-c1c(F)cccc1Cl. References: Works MG, et al. Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis. J Immunol. 2014 Oct 1,193(7):3278-87.
| Keywords: | SAR20347 |
| Supplier: | TargetMol |
| Supplier-Nr: | T4210 |
Properties
| Application: | JAK family kinase inhibitor |
| MW: | 444.84 D |
| Formula: | C21H18ClFN4O4 |
Database Information
| CAS : | 1450881-55-6| Matching products |
| KEGG ID : | K11219 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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