SAICAR (hydrate)

SAICAR is an intermediate in the de novo purine nucleotide synthesis pathway. It is reported to stimulate pyruvate kinase isoform M2 and to promote cancer cell survival in conditions of limited glucose availability.Formal Name: N-[[5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-4-yl]carbonyl]-L-aspartic acid, hydrate. Synonyms: Succino-AICAR, Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5'-phosphate. Molecular Formula: C13H19N4O12P . XH2O. Formula Weight: 454.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Slightly Soluble, Water: Slightly Soluble. SMILES: NC1=C(C(N[C@H](C(O)=O)CC(O)=O)=O)N=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O2.O. InChi Code: InChI=1S/C13H19N4O12P.H2O/c14-10-7(11(22)16-4(13(23)24)1-6(18)19)15-3-17(10)12-9(21)8(20)5(29-12)2-28-30(25,26)27,/h3-5,8-9,12,20-21H,1-2,14H2,(H,16,22)(H,18,19)(H,23,24)(H2,25,26,27),1H2/t4-,5+,8+,9+,12+,/m0./s1. InChi Key: HDXONPSAWBEBTQ-GMXQVFHASA-N.