Safranal

Safranal is a monoterpenoid that has been found in C. sativus and has diverse biological activities, including microtubule polymerization inhibitory, cancer cell growth inhibitory, and antioxidant properties. It decreases microtubule polymerization in a cell-free assay (IC50 = 72.19 µM) and inhibits the growth of HeLa cells (IC50 = 95 µM). Safranal (145.5, 363.75, and 727.5 mg/kg) reduces the levels of thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) in the hippocampus in a rat model of global cerebral ischemia. It also reduces convulsions induced by pentylenetetrazole (Cay-18682) in mice.Formal Name: 2,6,6-trimethyl-1,3-cyclohexadiene-1-carboxaldehyde. CAS Number: 116-26-7. Molecular Formula: C10H14O. Formula Weight: 150.2. Purity: >98%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml. lambdamax: 230, 310 nm. SMILES: O=CC1=C(C)C=CCC1(C)C. InChi Code: InChI=1S/C10H14O/c1-8-5-4-6-10(2,3)9(8)7-11/h4-5,7H,6H2,1-3H3. InChi Key: SGAWOGXMMPSZPB-UHFFFAOYSA-N. Origin: Synthetic.