Saclofen
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Saclofen is a sulfonic analog of the inhibitory neurotransmitter gamma-aminobutyric... more
Product information "Saclofen"
Description: Saclofen is a sulfonic analog of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 µM).1 This compound can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain. Target: GABA Receptor. Smiles: NCC(CS(O)(=O)=O)c1ccc(Cl)cc1. References: Drew C A, Johnston G A R, Kerr D I B, et al. Inhibition of baclofen binding to rat cerebellar membranes by phaclofen, saclofen, 3-aminopropylphosphonic acid and related GABAB receptor antagonists[J]. Neuroscience letters, 1990, 113(1): 107-110.
| Supplier: | TargetMol |
| Supplier-Nr: | T4440 |
Properties
| Application: | Competitive GABAB receptor antagonist |
| MW: | 249.71 D |
| Formula: | C9H12ClNO3S |
Database Information
| CAS : | 125464-42-8| Matching products |
| KEGG ID : | K04615 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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