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Description: S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (sigma1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2 receptor (sigma2R, Ki > 1000 nM). Target: Sigma receptor. Smiles: Cc1cc(OCCN2CCOCC2)nn1-c1ccc2ccccc2c1. References: Díaz JL, et al. J Med Chem. 2012 Oct 11,55(19): 8211-24.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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