Rucaparib
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose... more
Product information "Rucaparib"
Description: Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC). Target: PARP. Smiles: O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1. References: Thomas HD,etal.Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.Mol Cancer Ther. 2007 Mar,6(3):945-56.
| Keywords: | AG014699, AG-14447, PF-01367338 |
| Supplier: | TargetMol |
| Supplier-Nr: | T4463 |
Properties
| Application: | Targets poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] (PARP1) |
| MW: | 323.36 D |
| Formula: | C19H18FN3O |
Database Information
| CAS : | 283173-50-2| Matching products |
| KEGG ID : | K10798 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H361 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed