Ruboxistaurin hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective... more
Product information "Ruboxistaurin hydrochloride"
Description: Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC), competitively and reversibly inhibits PKCbetaI and PKCbetaII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCbeta over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 µM for PKCeta, -delta, -gamma, -alpha, -epsilon and -zeta respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src). Target: PKC. Smiles: Cl.CN(C)CC1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21. References: Jirousek MR, et al. J Med Chem. 1996, 39(14):2664-71.
| Keywords: | LY 333531 hydrochloride, LY333531 HCl, Ruboxistaurin |
| Supplier: | TargetMol |
| Supplier-Nr: | T3689 |
Properties
| Application: | PKCbeta inhibitor |
| MW: | 505.01 D |
| Formula: | C28H28N4O3·HCl |
Database Information
| CAS : | 169939-93-9| Matching products |
| KEGG ID : | K02677 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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