RU.521

Item number	Size	Manual	Delivery time	Price
TGM-T5486-1mg	1 mg	-	7 - 10 business days*	41.00€
TGM-T5486-2mg	2 mg	-	7 - 10 business days*	57.00€
TGM-T5486-1mL	1 ml	-	7 - 10 business days*	95.00€
TGM-T5486-5mg	5 mg	-	7 - 10 business days*	95.00€
TGM-T5486-10mg	10 mg	-	7 - 10 business days*	168.00€
TGM-T5486-25mg	25 mg	-	7 - 10 business days*	275.00€
TGM-T5486-50mg	50 mg	-	7 - 10 business days*	387.00€
TGM-T5486-100mg	100 mg	-	7 - 10 business days*	577.00€

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Description: RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the... more

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Product information "RU.521"

Description: RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS. Target: DNA, cGAS. Smiles: Cc1nn(c(O)c1C1OC(=O)c2ccccc12)-c1nc2ccc(Cl)c(Cl)c2[nH]1. References: Vincent J, et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun. 2017 Sep 29,8(1):750.

Keywords:	RU320521
Supplier:	TargetMol
Supplier-Nr:	T5486

Properties

Application:	cGAS inhibitor
MW:	415.23 D
Formula:	C19H12Cl2N4O3

Database Information

CAS :	2262452-06-0\| Matching products
KEGG ID :	K17834 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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