RS 504393
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and... more
Product information "RS 504393"
Description: RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 µM for human recombinant CCR2 and CCR1). Target: CCR. Smiles: Cc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1. References: Mirzadegan T, et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. J Biol Chem. 2000 Aug 18,275(33):25562-71.
| Supplier: | TargetMol |
| Supplier-Nr: | T5384 |
Properties
| Application: | CCR2 chemokine receptor antagonist |
| MW: | 417.5 D |
| Formula: | C25H27N3O3 |
Database Information
| CAS : | 300816-15-3| Matching products |
| KEGG ID : | K04177 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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