Rosuvastatin-d6 (sodium salt)

Rosuvastatin-d6 (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay23359-500 500 µg -

6 - 10 business days*

267.00€
Cay23359-1 1 mg -

6 - 10 business days*

426.00€
Cay23359-5 5 mg -

6 - 10 business days*

1,999.00€
 
Rosuvastatin-d6 is intended for use as an internal standard for the quantification of... more
Product information "Rosuvastatin-d6 (sodium salt)"
Rosuvastatin-d6 is intended for use as an internal standard for the quantification of rosuvastatin (Cay-12029, Cay-18813) by GC- or LC-MS. Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the area of aortic atherosclerotic lesions in the same model. Formulations containing rosuvastatin have been used in the treatment of dyslipidemias.Formal Name: (3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate, monosodium salt. CAS Number: 2070009-41-3. Molecular Formula: C22H21D6FN3O6S . Na. Formula Weight: 509.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: O[C@@H](C[C@H](CC([O-])=O)O)/C=C/C(C(C1=CC=C(F)C=C1)=NC(N(C)[S](C)(=O)=O)=N2)=C2C(C([2H])([2H])[2H])C([2H])([2H])[2H].[Na+]. InChi Code: InChI=1S/C22H28FN3O6S.Na/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32,/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30),/q,+1/p-1/b10-9+,/t16-,17-,/m1./s1/i1D3,2D3,. InChi Key: RGEBGDYYHAFODH-HPECXWNWSA-M.
Keywords: (3R,5S,E)-7-(4-(4-fluorophenyl)-2-(N-methylmethylsulfonamido)-6-(propan-2-yl-1,1,1,3,3,3-d6)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 23359

Properties

Application: GC-MS, LC-MS, internal standard, HMG-CoA reductase inhibitor
MW: 509.6 D
Formula: C22H21D6FN3O6S . Na
Purity: >98%
Format: Solid

Database Information

CAS : 2070009-41-3| Matching products
KEGG ID : K00021 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P330, P301+P310, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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