Roflumilast
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of... more
Product information "Roflumilast"
Description: Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling. Target: PDE, RSV. Smiles: O(CC1CC1)C2=C(OC(F)F)C=CC(C(NC=3C(Cl)=CN=CC3Cl)=O)=C2. References: Hatzelmann A, et al. Pulm Pharmacol Ther, 2010, 23(4), 235-256.
| Keywords: | BYK 20869, B9302-107, APTA 2217, BY 217 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1024 |
Properties
| MW: | 403.21 D |
| Formula: | C17H14Cl2F2N2O3 |
Database Information
| CAS : | 162401-32-3| Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed