Ro 90-7501
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Ro 90-7501 is an amyloid beta42 (Abeta42) protofibrillar and TPR-dependent PP5... more
Product information "Ro 90-7501"
Description: Ro 90-7501 is an amyloid beta42 (Abeta42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer activity by inhibiting ATM phosphorylation and DNA repair, and by inhibiting HCMV. Target: Phosphatase, ATM/ATR, Apoptosis, Gamma-secretase. Smiles: NC1=CC=C(C=C1)C1=NC2=C(N1)C=C(C=C2)C1=NC2=C(N1)C=C(N)C=C2. References: Guo F, et al. RO 90-7501 enhances TLR3 and RLR agonist induced antiviral response. PLoS One. 2012,7(10):e42583.
| Keywords: | RO-90-7501 |
| Supplier: | TargetMol |
| Supplier-Nr: | T16773 |
Properties
| Application: | Abeta42 fibril assembly inhibitor, TLR3 signaling modulator |
| MW: | 340.38 D |
| Formula: | C20H16N6 |
Database Information
| CAS : | 293762-45-5| Matching products |
| KEGG ID : | K04520 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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