Rimiducid
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of... more
Product information "Rimiducid"
Description: Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis. Target: Others, Apoptosis, Fatty Acid Synthase. Smiles: CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)NCCNC(=O)COc2cccc(c2)[C@@H](CCc2ccc(OC)c(OC)c2)OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](CC)c2cc(OC)c(OC)c(OC)c2)c1)c1cc(OC)c(OC)c(OC)c1. References: Clackson T, et al. Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci U S A. 1998 Sep 1,95(18):10437-42.
| Supplier: | TargetMol |
| Supplier-Nr: | T14298 |
Properties
| Application: | Targets caspase 9 [EC:3.4.22.62] (CASP9) |
| MW: | 1411.63 D |
| Formula: | C78H98N4O20 |
Database Information
| CAS : | 195514-63-7| Matching products |
| KEGG ID : | K04399 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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