Rifapentine

Rifapentine is a long-lasting rifamycin antibiotic that inhibits DNA-dependent RNA polymerases and is effective against Mycobacterium species, including M. tuberculosis, as well as experimental infections caused by S. aureus, S. pyogenes group A, S. pneumoniae, and K. pneumoniae.Formal Name: 3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-rifamycin. CAS Number: 61379-65-5. Synonyms: Cyclopentylrifampicin, DL-473, MDL 473. Molecular Formula: C47H64N4O12. Formula Weight: 877.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml, Ethanol: 2 mg/ml. lambdamax: 237, 253, 336, 478 nm. SMILES: OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C6CCCC6)CC5. InChi Code: InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38. InChi Key: WDZCUPBHRAEYDL-GZAUEHORSA-N.