Resveratrol-3-O-Sulfate (sodium salt)

Resveratrol-3-O-Sulfate (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14942-500 500 µg -

6 - 10 business days*

257.00€
Cay14942-1 1 mg -

6 - 10 business days*

465.00€
 
Resveratrol-3-O-sulfate is a metabolite of resveratrol (Cay-70675, Cay-10004235). In U-937 cells... more
Product information "Resveratrol-3-O-Sulfate (sodium salt)"
Resveratrol-3-O-sulfate is a metabolite of resveratrol (Cay-70675, Cay-10004235). In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 µM) decreases the expression of IL-1alpha, IL-1beta, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-alpha and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 µM, and induces apoptosis at concentrations of 25 and 50 µM. Resveratrol-3-O-sulfate also displaces rosiglitazone (Cay-71740) from the outer mitochondrial protein mitoNEET (IC50 = 3.36 µM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.Formal Name: 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, 1-(hydrogen sulfate), monosodium salt. CAS Number: 858127-11-4. Molecular Formula: C14H11O6S . Na. Formula Weight: 330.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly Soluble. SMILES: O=S(OC1=CC(O)=CC(/C=C/C2=CC=C(O)C=C2)=C1)([O-])=O.[Na+]. InChi Code: InChI=1S/C14H12O6S.Na/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(8-11)20-21(17,18)19,/h1-9,15-16H,(H,17,18,19),/q,+1/p-1/b2-1+,. InChi Key: OWGXRCOCVOPKAM-TYYBGVCCSA-M.
Keywords: 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, 1-(hydrogen sulfate), monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 14942

Properties

Application: trans-Resveratrol metabolite
MW: 330.3 D
Formula: C14H11O6S . Na
Purity: >95%

Database Information

CAS : 858127-11-4| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319, H341
P Phrases: P201, P202, P264, P280, P305+P351+P338, P308+P313, P337+P313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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