Reparixin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it... more
Product information "Reparixin"
Description: Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM). Target: CXCR. Smiles: CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O. References: Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem. 2007 Aug 23,50(17):3984-4002.
| Keywords: | DF 1681Y, Repertaxin |
| Supplier: | TargetMol |
| Supplier-Nr: | T4163 |
Properties
| Application: | Targets C-X-C chemokine receptor type 1 (CXCR1, IL8RA, CD181) |
| MW: | 283.39 D |
| Formula: | C14H21NO3S |
Database Information
| CAS : | 266359-83-5| Matching products |
| KEGG ID : | K04175 | Matching products |
| Protein Atlas Nr. : | GPCR Modulators/A(nta)gonists |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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