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Description: Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively). Target: Others. Smiles: C(C=1C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=NN(C(C)C)C1C)C3=CC=C(OC(C)C)C=C3. References: Sadurní A, Kehr G, Ahlqvist M, Wernevik J, Sjögren HP, Kankkonen C, Knerr L, Gilmour R. Fluorine-Directed Glycosylation Enables the Stereocontrolled Synthesis of Selective SGLT2 Inhibitors for Type II Diabetes. Chemistry. 2018 Feb 26,24(12):2832-2836. doi: 10.1002/chem.201705373. Epub 2017 Dec 20. PubMed PMID: 29211300.
Keywords:
GSK189074, Remogliflozin A, GSK-189074, GSK 189074
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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