Rapamycin
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with... more
Product information "Rapamycin"
Description: Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy. Target: Autophagy, Antibiotic, mTOR, Antifungal, Endogenous Metabolite, Others. Smiles: [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC. References: Pallet N, et al. Rapamycin inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability. Kidney Int. 2005 Jun,67(6):2422-33.
| Keywords: | NSC-2260804, AY 22989, Sirolimus |
| Supplier: | TargetMol |
| Supplier-Nr: | T1537 |
Properties
| Application: | Targets serine/threonine-protein kinase mTOR [EC:2.7.11.1] (MTOR, FRAP, TOR) |
| MW: | 914.17 D |
| Formula: | C51H79NO13 |
Database Information
| CAS : | 53123-88-9| Matching products |
| KEGG ID : | K07203 | Matching products |
| Protein Atlas Nr. : | Ser/Thr Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H351, H361, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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