(Rac)-SIS3 free base

(Rac)-SIS3 free base
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T12923-25mg 25 mg

7 - 10 business days*

732.00€
TGM-T12923-50mg 50 mg

7 - 10 business days*

955.00€
TGM-T12923-100mg 100 mg

7 - 10 business days*

1,530.00€
 
Description: SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation,... more
Product information "(Rac)-SIS3 free base"
Description: SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-beta1-induced myofibroblast differentiation of fibroblasts. Target: TGF-beta/Smad. Smiles: COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12. References: Jinnin M, et al. Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol. 2006 Feb,69(2):597-607. Epub 2005 Nov 15.
Supplier: TargetMol
Supplier-Nr: T12923

Properties

Application: Smad3 phosphorylation inhibitor
MW: 453.53 D
Formula: C28H27N3O3

Database Information

CAS : 1009104-85-1| Matching products
KEGG ID : K04500 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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