rac-Hesperetin-d3

rac-Hesperetin-d3 is intended for use as an internal standard for the quantification of hesperetin (Cay-10006084) by GC- or LC-MS. rac-Hesperetin is a racemic mixture of the flavanones (S)-hesperetin (Cay-10006084) and (R)-hesperetin. rac-Hesperetin (1 mM) inhibits heat-induced advanced glycation end product formation between BSA and glucose by 56.7%. It also inhibits alpha-glucosidase and protein tyrosine phosphatase 1B (PTP1B, IC50s = 15.28 and 20.16 µM, respectively). rac-Hesperetin (100 µM) protects against hydrogen peroxide-induced cytotoxicity in MIN6 pancreatic beta cells by 72.27%.Formal Name: 5,7-dihydroxy-2-(3-hydroxy-4-(methoxy-d3)phenyl)chroman-4-one. CAS Number: 1346605-26-2. Synonyms: (±)-3',5,7-Trihydroxy-4'-methoxyflavanone-d3. Molecular Formula: C16H11D3O6. Formula Weight: 305.3. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: Methanol: slightly soluble. SMILES: OC1=C(OC([2H])([2H])[2H])C=CC(C2CC(C3=C(O)C=C(O)C=C3O2)=O)=C1. InChi Code: InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/i1D3. InChi Key: AIONOLUJZLIMTK-FIBGUPNXSA-N. Origin: Synthetic.