R1487 Hydrochloride

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T7162-2mg	2 mg				7 - 10 business days*		65.00€
TGM-T7162-5mg	5 mg				7 - 10 business days*		105.00€

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Description: R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly... more

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Product information "R1487 Hydrochloride"

Description: R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38alpha. Target: Autophagy, p38 MAPK. Smiles: Cl.Cn1c2nc(NC3CCOCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O. References: Goldstein DM, Soth M, Gabriel T,et al.Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38alpha mitogen-activated protein kinase[J].J Med Chem. 2011 Apr 14,54(7):2255-65.

Keywords:	R1487 (Hydrochloride)
Supplier:	TargetMol
Supplier-Nr:	T7162

Properties

Application:	p38alpha / MAPK14 inhibitor
MW:	424.83 D
Formula:	C19H19ClF2N4O3

Database Information

CAS :	449808-64-4\| Matching products
KEGG ID :	K04441 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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