L-Phenylephrine (hydrochloride)

L-Phenylephrine is an adrenergic alpha1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the alpha1B and alpha1C receptor subtypes (Kis = 23.9 and 47.8 µM, respectively). By stimulating adrenergic alpha1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine (Cay-16673). This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents.Formal Name: 3-hydroxy-alpha-[(methylamino)methyl]-benzenemethanol, monohydrochloride. CAS Number: 61-76-7. Synonyms: (R)-(-)-Phenylephrine. Molecular Formula: C9H13NO2 . HCl. Formula Weight: 203.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 216, 276 nm. SMILES: OC1=CC=CC([C@@H](O)CNC)=C1.Cl. InChi Code: InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7,/h2-5,9-12H,6H2,1H3,1H/t9-,/m0./s1. InChi Key: OCYSGIYOVXAGKQ-FVGYRXGTSA-N.