Quinacrine (dihydrochloride hydrate)

Description: Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 µM) and suppresses aldehyde oxidase (IC50: 3.3 µM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 µM). As an effective riboflavin antagonist, quinacrine associates with the riboflavin-binding protein (Ki: 6.7 µM). Voltage-dependent sodium channels play a vital role in action potential initiation and propagation in excitable cells, including muscle, nerve, and neuroendocrine cell types. Target: Others. Smiles: ClC1=CC=C2C(NC(C)CCCN(CC)CC)=C3C(C=CC(OC)=C3)=NC2=C1.Cl.Cl.O