Purpurin

Purpurin is a naturally occurring reddish-yellow pigment found in madder root (R. tinctorum) that has been used both in herbal remedies and as food coloring. It can also be synthetically derived from 9,10-anthraquinone. Purpurin is protective against a number of food-derived heterocyclic amines in bacterial mutagenicity assays through its inhibition of CYP450-dependent N-hydroxylation and reduction of N-hydroxylamines. Purpurine can also inhibit (IC50 = 6.6 µM) spermidine-induced autoactivation of plasma hyaluronan-binding protein, a serine protease that can activate coagulation factor VII and prourokinase.Formal Name: 1,2,4-trihydroxy-9,10-anthracenedione. CAS Number: 81-54-9. Synonyms: Hydroxylizaric Acid, NSC 10447, Verantin. Molecular Formula: C14H8O5. Formula Weight: 256.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 0.5 mg/ml. lambdamax: 255, 484 nm. SMILES: O=C1C2=C(O)C=C(O)C(O)=C2C(C3=C1C=CC=C3)=O. InChi Code: InChI=1S/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19H. InChi Key: BBNQQADTFFCFGB-UHFFFAOYSA-N. Origin: Synthetic.