Pomalidomide 4'-PEG5-amine (hydrochloride)

Pomalidomide 4'-PEG5-amine is a PEGylated form of the cereblon (CRBN) inhibitor pomalidomide (Cay-19877). It has been conjugated to various ligands in the development of proteolysis-targeting chimeras (PROTACs).Formal Name: 4-[(17-amino-3,6,9,12,15-pentaoxaheptadec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, monohydrochloride. CAS Number: 2357117-23-6. Molecular Formula: C25H36N4O9 . HCl. Formula Weight: 573.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Sparingly Soluble: 1-10 mg/ml. SMILES: O=C(N1C(CCC2=O)C(N2)=O)C(C(C1=O)=CC=C3)=C3NCCOCCOCCOCCOCCOCCN.Cl. InChi Code: InChI=1S/C25H36N4O9.ClH/c26-6-8-34-10-12-36-14-16-38-17-15-37-13-11-35-9-7-27-19-3-1-2-18-22(19)25(33)29(24(18)32)20-4-5-21(30)28-23(20)31,/h1-3,20,27H,4-17,26H2,(H,28,30,31),1H. InChi Key: OOFYLIGYAMKSRB-UHFFFAOYSA-N.