PNU-74654
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the... more
Product information "PNU-74654"
Description: PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Target: Apoptosis, Wnt/beta-catenin. Smiles: Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1. References: Leal, Letícia F, Bueno A C , Gomes, Débora C, et al. Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis[J]. Oncotarget, 2015, 6(40).
| Supplier: | TargetMol |
| Supplier-Nr: | T7204 |
Properties
| Application: | Tcf4/beta-catenin interaction inhibitor |
| MW: | 320.34 D |
| Formula: | C19H16N2O3 |
Database Information
| CAS : | 113906-27-7| Matching products |
| KEGG ID : | K02105 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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