PLX-4720

PLX-4720
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T2473-5mg 5 mg

7 - 10 business days*

33.00€
TGM-T2473-1mL 1 ml

7 - 10 business days*

42.00€
TGM-T2473-10mg 10 mg

7 - 10 business days*

48.00€
TGM-T2473-25mg 25 mg

7 - 10 business days*

79.00€
TGM-T2473-50mg 50 mg

7 - 10 business days*

100.00€
TGM-T2473-100mg 100 mg

7 - 10 business days*

125.00€
 
Description: PLX-4720, a potent and selective inhibitor of B-Raf (V600E) with an IC50 of 13 nM,... more
Product information "PLX-4720"
Description: PLX-4720, a potent and selective inhibitor of B-Raf (V600E) with an IC50 of 13 nM, is equally effective against c-Raf-1 (Y340D and Y341D mutations). Target: Raf. Smiles: CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F. References: Tsai J, et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A, 2008, 105(8), 3041-3046.
Keywords: PLX4720
Supplier: TargetMol
Supplier-Nr: T2473

Properties

Application: B-Raf (V600E) / c-Raf-1 (Y340D/Y341D) inhibitor
MW: 413.83 D
Formula: C17H14ClF2N3O3S

Database Information

CAS : 918505-84-7| Matching products
KEGG ID : K04365 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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