Plumbagin

Plumbagin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14314-100 100 mg -

6 - 10 business days*

49.00€
Cay14314-250 250 mg -

6 - 10 business days*

74.00€
Cay14314-500 500 mg -

6 - 10 business days*

130.00€
 
Plumbagin is a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago. It... more
Product information "Plumbagin"
Plumbagin is a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago. It has diverse effects in cells and animals. Plumbagin causes the generation of reactive oxygen species and induces apoptosis in cancer cells. It activates signaling through Nrf2 and the antioxidant response element, inducing the expression of Nrf2 target genes, including NQO1 and heme oxygenase-1 in cultured neuronal cells. Plumbagin also inhibits NADPH oxidase 4 in a time- and dose-dependent manner. It can be protective against peroxide stress or deprivation of glucose or oxygen.Formal Name: 5-hydroxy-2-methyl-1,4-naphthalenedione. CAS Number: 481-42-5. Synonyms: NSC 236613, NSC 688284. Molecular Formula: C11H8O3. Formula Weight: 188.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 10 mg/ml, Ethanol: 5 mg/ml, Methanol: 5 mg/ml. lambdamax: 210, 264 nm. SMILES: CC1=CC(C(C(O)=CC=C2)=C2C1=O)=O. InChi Code: InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3. InChi Key: VCMMXZQDRFWYSE-UHFFFAOYSA-N.
Keywords: NSC 236613, NSC 688284, 5-hydroxy-2-methyl-1,4-naphthalenedione
Supplier: Cayman Chemical
Supplier-Nr: 14314

Properties

Application: Nrf2 activator
MW: 188.2 D
Formula: C11H8O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 481-42-5| Matching products
KEGG ID : K05638 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H314, H318
P Phrases: P260, P264, P270, P280, P321, P363, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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