Plevitrexed

Item number	Size	Delivery time	Price
TGM-T12635L-25mg	25 mg	7 - 10 business days*	3,323.00€
TGM-T12635L-50mg	50 mg	7 - 10 business days*	4,386.00€
TGM-T12635L-100mg	100 mg	7 - 10 business days*	6,109.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Description: Plevitrexed is taken up via the alpha-folate receptor as well as the reduced folate... more

Close menu

Product information "Plevitrexed"

Description: Plevitrexed is taken up via the alpha-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric cancer in clinical. Target: Others. Smiles: O=C1C=2C(=CC(C)=C(CN(CC#C)C3=CC(F)=C(C(N[C@@H](CCC=4NN=NN4)C(O)=O)=O)C=C3)C2)NC(C)=N1. References: Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-gamma-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem. 2013 Jul 11,56(13):5446-55.

Keywords:	BGC9331, ZD 9331
Supplier:	TargetMol
Supplier-Nr:	T12635L

Properties

Application:	Targets thymidylate synthase [EC:2.1.1.45] (thyA, TYMS)
MW:	532.53 D
Formula:	C26H25FN8O4
Format:	32160405

Database Information

CAS :	153537-73-6\| Matching products
KEGG ID :	K00560 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "Plevitrexed"

Write a review