Picamilon

Picamilon is a derivative of gamma-aminobutyric acid (GABA). It increases parietal cortical blood flow in rats and rabbits when administered at doses of 50 mg/kg, i.p. and 10 mg/kg, i.v., respectively. Picamilon (10 mg/kg) increases latency to enter the dark compartment in the passive avoidance conditioned reflex test in rats compared with control animals, indicating nootropic effects.Formal Name: 4-[(3-pyridinylcarbonyl)amino]-butanoic acid. CAS Number: 34562-97-5. Synonyms: Nicotinoyl-GABA. Molecular Formula: C10H12N2O3. Formula Weight: 208.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, DMSO:PBS (pH 7.2) (1:9): 0.10 mg/ml. SMILES: O=C(NCCCC(O)=O)C1=CN=CC=C1. InChi Code: InChI=1S/C10H12N2O3/c13-9(14)4-2-6-12-10(15)8-3-1-5-11-7-8/h1,3,5,7H,2,4,6H2,(H,12,15)(H,13,14). InChi Key: NAJVRARAUNYNDX-UHFFFAOYSA-N.