Phorbol 12-myristate 13-acetate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of... more
Product information "Phorbol 12-myristate 13-acetate"
Description: Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of natural products, activates PKC, SphK, and NF-kappaB, and induces THP1 cell differentiation. Target: PKC, S1P Receptor, NF-kappaB. Smiles: [H][C@]12[C@]3([H])C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@]4([H])[C@@]3(O)[C@H](C)[C@@H](OC(=O)CCCCCCCCCC CCC)[C@@]1(OC(C)=O)C2(C)C. References: Jørgensen K, et al. Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2. Biochem Biophys Res Commun. 2005 Apr 1,329(1):266-74.
| Keywords: | PMA |
| Supplier: | TargetMol |
| Supplier-Nr: | TQ0198 |
Properties
| Application: | PKC activator |
| MW: | 616.83 D |
| Formula: | C36H56O8 |
Database Information
| CAS : | 16561-29-8| Matching products |
| KEGG ID : | K02677 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315 |
| P Phrases: | P264, P280, P302+352, P321, P332+313, P362+364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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