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Product information "Phorbol 12-myristate 13-acetate"
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16, Potent mouse skin tumor promoter, Promoter of inducible NOS (iNOS, NOS II), Apoptosis inducer, Potential effective cancer therapeutic agent, Inhibitor of anti-lipolytic activity of insulin. Semisynthetic.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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