PF-543 hydrochloride

Item number	Size	Delivery time	Price
TGM-T8840-1mg	1 mg	7 - 10 business days*	33.00€
TGM-T8840-5mg	5 mg	7 - 10 business days*	69.00€
TGM-T8840-1mL	1 ml	7 - 10 business days*	103.00€
TGM-T8840-10mg	10 mg	7 - 10 business days*	134.00€
TGM-T8840-25mg	25 mg	7 - 10 business days*	242.00€
TGM-T8840-50mg	50 mg	7 - 10 business days*	328.00€
TGM-T8840-100mg	100 mg	7 - 10 business days*	502.00€

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Description: PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is... more

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Product information "PF-543 hydrochloride"

Description: PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. Target: Autophagy, S1P Receptor, Apoptosis, LPL Receptor. Smiles: Cl.Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1. References: Schnute ME, McReynolds MD, Kasten T, et al. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. Biochem J. 2012,444(1):79-88. doi:10.1042/BJ20111929

Keywords:	PF-543
Supplier:	TargetMol
Supplier-Nr:	T8840

Properties

Application:	Sphingosine kinase 1 inhibitor
MW:	502.1 D
Formula:	C27H32ClNO4S

Database Information

CAS :	1706522-79-3\| Matching products
KEGG ID :	K04718 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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