PF-2545920
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Solid. Soluble in DMSO or ethanol. Insoluble in water. Potent and selective phosphodiesterase 10A... more
Product information "PF-2545920"
Solid. Soluble in DMSO or ethanol. Insoluble in water. Potent and selective phosphodiesterase 10A (PDE10A) inhibitor (IC50=1.26nM) in vitro and in vivo. PDE10A is a cGMP and cAMP degrading PDE isozyme with neurological importance and was shown to be implicated in the regulation of energy homeostasis. Inhibition of PDE10A leads to interference of the breakdown of the secondary messenger cAMP and cGMP, Anti-psychotic agent. Useful for the treatment of schizophrenia, Anticancer agent. Inhibits colon tumor cell growth for which high levels of PDE10A have been reported, Antiobesity and antidiabetic agent. Induces browning in white adipose tissue (WAT).
| Keywords: | 2-(4-(1-Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)-phenoxymethyl)quinoline, MP-10 |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CR1-3636 |
Properties
| Application: | PDE10A inhibitor |
| MW: | 392,5 D |
| Formula: | C25H20N4O |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 898562-94-2| Matching products |
| KEGG ID : | K18438 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H319 |
| P Phrases: | P270, P280, P330, P301+P312, P305+P351+P338, P337+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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