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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay22066-500 | 500 µg | - |
6 - 10 business days* |
254.00€
|
|||
| Cay22066-2.5 | 2500 µg | - |
6 - 10 business days* |
1,007.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PF-1163B is a depsipeptide antifungal isolated from Penicillium that inhibits ergosterol (ERG)... more
Product information "PF-1163B"
PF-1163B is a depsipeptide antifungal isolated from Penicillium that inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). It inhibits growth of C. albicans (MIC = 32 µg/ml) but not of other Candida strains, A. fumigatus, or HepG2 cells. It acts synergistically with fluconazole (Cay-11594) to reduce growth of azole-resistant C. albicans (MIC = 2 and 0.0016 µg/ml alone and in combination, respectively). PF-1163B is a hydroxy form of PF-1163A (Cay-22065).Formal Name: 3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione. CAS Number: 258871-60-2. Molecular Formula: C27H43NO5. Formula Weight: 461.6. Purity: >95%. Formulation: (Request formulation change), An oil. Solubility: Acetonitrile: Soluble. SMILES: O=C(N(C)[C@H]1CC2=CC=C(OCCO)C=C2)CCCC[C@@H](C)CC[C@@H](CCCCC)OC1=O. InChi Code: InChI=1S/C27H43NO5/c1-4-5-6-10-24-15-12-21(2)9-7-8-11-26(30)28(3)25(27(31)33-24)20-22-13-16-23(17-14-22)32-19-18-29/h13-14,16-17,21,24-25,29H,4-12,15,18-20H2,1-3H3/t21-,24-,25+/m1/s1. InChi Key: PCRJJAXIHTZHNU-SDUSCBPUSA-N. Origin: Fungus/Unidentified sp..
| Keywords: | 3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 22066 |
Properties
| Application: | Ergosterol synthesis inhibitor |
| MW: | 461.6 D |
| Formula: | C27H43NO5 |
| Purity: | >95% |
| Format: | Liquid |
Database Information
| CAS : | 258871-60-2| Matching products |
| KEGG ID : | K07750 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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