PF-00835231

Item number	Size	Delivery time	Price
TGM-T9458-1mg	1 mg	7 - 10 business days*	52.00€
TGM-T9458-2mg	2 mg	7 - 10 business days*	74.00€
TGM-T9458-5mg	5 mg	7 - 10 business days*	122.00€
TGM-T9458-1mL	1 ml	7 - 10 business days*	134.00€
TGM-T9458-10mg	10 mg	7 - 10 business days*	195.00€
TGM-T9458-25mg	25 mg	7 - 10 business days*	381.00€
TGM-T9458-50mg	50 mg	7 - 10 business days*	618.00€
TGM-T9458-100mg	100 mg	7 - 10 business days*	891.00€

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Description: PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of... more

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Product information "PF-00835231"

Description: PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials. Target: SARS-CoV. Smiles: COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO. References: Robert L Hoffman, et al. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 Nov 12,63(21):12725-12747.

Supplier:	TargetMol
Supplier-Nr:	T9458

Properties

Application:	SARS-CoV / SARS-CoV-2 Mpro inhibitor
MW:	472.53 D
Formula:	C24H32N4O6

Database Information

CAS :	870153-29-0\| Matching products
KEGG ID :	K25015 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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