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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T62788-2mg | 2 mg | - |
7 - 10 business days* |
31.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally... more
Product information "Pexidartinib hydrochloride"
Description: Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally active, ATP-competitive inhibitor of colony-stimulating factor 1 (CSF1R or M-CSFR) (IC50: 20 nM) and c-Kit (IC50: 10 nM), with 10-100 times greater selectivity for these targets compared to FLT3 (IC50: 160 nM), KDR (VEGFR2) (IC50: 350 nM), and LCK (IC50: 860 nM). Pexidartinib hydrochloride induces apoptosis and exhibits anti-tumor effects. Target: Others. Smiles: Cl.FC(F)(F)c1ccc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)cn2)cn1
| Supplier: | TargetMol |
| Supplier-Nr: | T62788 |
Properties
| Application: | Targets macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1] (CSF1R, FMS, CD115) |
| MW: | 454.28 D |
| Formula: | C20H16Cl2F3N5 |
Database Information
| CAS : | 2040295-03-0| Matching products |
| KEGG ID : | K05090 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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