PCO371

Item number	Size	Delivery time	Price
TGM-T16442-1mg	1 mg	7 - 10 business days*	97.00€
TGM-T16442-5mg	5 mg	7 - 10 business days*	245.00€
TGM-T16442-1mL	1 ml	7 - 10 business days*	345.00€
TGM-T16442-10mg	10 mg	7 - 10 business days*	395.00€
TGM-T16442-25mg	25 mg	7 - 10 business days*	660.00€
TGM-T16442-50mg	50 mg	7 - 10 business days*	944.00€
TGM-T16442-100mg	100 mg	7 - 10 business days*	1,281.00€

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Description: PCO371 (2,4-Imidazolidinedione,... more

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Product information "PCO371"

Description: PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor. Target: Thyroid hormone receptor(THR). Smiles: Cc1cc(cc(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(NC2=O)c1ccc(OC(F)(F)F)cc1)N1C(=O)NC(=O)C1(C)C. References: Tamura T, et al. Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism. Nat Commun. 2016 Nov 18,7:13384.

Keywords:	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
Supplier:	TargetMol
Supplier-Nr:	T16442

Properties

Application:	PTH1R agonist
MW:	635.65 D
Formula:	C29H32F3N5O6S

Database Information

CAS :	1613373-33-3\| Matching products
KEGG ID :	K04585 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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