PCI-32765
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PCI-32765 is an irreversible inhibitor of Bruton's tyrosine kinase (BTK), an enzyme that plays a... more
Product information "PCI-32765"
PCI-32765 is an irreversible inhibitor of Bruton's tyrosine kinase (BTK), an enzyme that plays a significant role in B-cell receptor signaling and B-cell malignancies and autoimmune diseases such as x-linked agammaglobulinemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma. PCI-32765's inhibition of BTK prevents IgE-mediated activation of basophils, inhibits signaling from macrophages and mast cells, and inhibits cell migration and survival in cellular and animal models of chronic lymphocytic leukemia. Additionally, PCI-32765 inhibits IL-2-inducible kinase.
| Keywords: | Ibrutinib |
| Supplier: | LKT Laboratories |
| Supplier-Nr: | P0932 |
Properties
| Application: | Bruton's tyrosine kinase inhibitor |
| MW: | 440.5 D |
| Purity: | >99% |
| Format: | Solid |
Database Information
| CAS : | 936563-96-1| Matching products |
| KEGG ID : | K07370 | Matching products |
Handling & Safety
| Storage: | +20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P280, P305+P351+P338, P321, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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