PBIT
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: PBIT inhibits JARID1B histone demethylase (IC50 of about 3 µM). PBIT also inhibits... more
Product information "PBIT"
Description: PBIT inhibits JARID1B histone demethylase (IC50 of about 3 µM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 µM and 4.9 µM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes . Target: Histone Methyltransferase, Histone Demethylase. Smiles: CC1=CC=C(C=C1)N1SC2=CC=CC=C2C1=O. References: Sayegh J, et al. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem. 2013 Mar 29,288(13):9408-17.
| Supplier: | TargetMol |
| Supplier-Nr: | T16435 |
Properties
| Application: | JARID1B inhibitor |
| MW: | 241.31 D |
| Formula: | C14H11NOS |
Database Information
| CAS : | 2514-30-9| Matching products |
| KEGG ID : | K11446 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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